No Approved Therapies

The development of vaccines, antibodies, and replication inhibitors is of paramount importance yet highly challenging and cost-prohibitive. In addition, all of these antiviral products suffer from two crucial problems: they do not work against multiple viruses and/or they lose efficacy against emerging drug-resistant virus strains.

There are currently also no approved therapies for most viral infections. Those that have made it to human clinical trials have had limited success and sub-optimal outcomes. Most of the standard treatment options remain merely supportive, focused on reducing symptoms as opposed to stopping the virus. Similar problem exists with filoviruses that represent bioterror threats, such as Ebola and Marburg. Also, despite the repeated appearance of different types of coronavirus (SARS, MERS and COVID-19) in the last two decades, there is no approved therapies against coronaviruses as of today.